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Company History

  • Our company roots go back to 1923, but our modern focus is on attending to our clients' needs and expectations.
  • Since 1923 Isolation and purification of insulin from bovine pancreas
  • Since 1930 Isolation and purification of insulin from porcine pancreas
  • From 1930 to 1963 Isolation and purification of gonadotropins Prolan A (Follicle Stimulating Hormone, FSH) and Prolan B (Lutenising Hormone, LH) from pituitary glands
  • From 1931 to 1966 Isolation and purification of Human Chorionic Gonadotropin (HCG) from human placenta
  • Since 1942 Isolation and purification of Adreno Corticotropic Hormone (ACTH) from pituitary glands
  • Since 1948 Isolation and purification of heparin from bovine lung
  • Since 1955 Isolation and purification of heparin from porcine mucosa
  • Since 1963 Isolation and purification of Human Menopausal Gonadotropin (HMG) from urine of menopausal women
  • Since 1966 Isolation and purification of Human Chorionic Gonadotropin (HCG) from urine of pregnant women
  • Since 1987 Isolation and purification of Hyaluronic Acid from rooster combs
  • Since 1995 Production of recombinant Follicle Stimulating Hormone (FSH)
  • 1995 Corning BioPro (now Diosynth RTP Inc.) founded as part of Corning Pharmaceutical Services
  • 1995 Groundbreaking on 109,000ft.2 (10,320 m2) dedicated multi-product cGMP production facility in RTP, North Carolina, USA
  • 1996 Official opening of Diosynth's new campus in Oss, the Netherlands
  • 1996 Corning Pharmaceutical Services spun-off as Covance, Inc. and Covance Biotechnology Services Inc. founded as a subsidiary
  • 1997 First clinical product shipped from the RTP facility, North Carolina, USA
  • 1998 First FDA inspection of Diosynth's recombinant protein facilities in Oss, the Netherlands, leads to marketed product
  • 1999 Diosynth begins process development of recombinant insulin
  • 2000 Formal opening of state-of-the-art cGMP downstream processing facility and official start of the upstream facility expansion in Oss, the Netherlands
  • 2001 May - First FDA inspection at RTP, North Carolina, USA, facility
  • 2001 June - Akzo Nobel Inc. acquires Covance Biotechnology Services Inc., forming Diosynth RTP Inc.
  • 2001 October - Announcement of additional investment in upstream facility in Oss, the Netherlands
  • 2002 October - Research Triangle Park (RTP), North Carolina, USA, facility hosts EMEA inspection
  • 2003 June – Diosynth Biotechnology signs multi-year contract with Pfizer Inc to produce commercial product
  • 2006 May – Diosynth Biotechnology incorporates a novel cell line development technology into its portfolio of offerings
  • 2007 November – Diosynth Biotechnology becomes a part of Schering-Plough Corporation 

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