Subscribe to our:Fermentation Development
In Fermentation, we have significant experience with E. coli cell lines and we have developed a leading position in the production of proteins from yeast systems such as Pichia.
E. coli Experience
- Inclusion bodies
- Cytoplasmic
- Periplasmic
Pichia pastoris Experience
- mut+, muts
- Secreted
- Intracellular
Flavobacterium
Streptococcus
Our scientists will select or develop media formulations (including serum-free and protein-free) and nutrient feed strategies to optimize cell growth and productivity. Once a process is developed at "bench scale" (typically using 10-L fermenters/bioreactors), it will be scaled-up to 110-L scale (mammalian processes) or 140-L scale (microbial processes). Our development infrastructure has been designed to match our clinical and commercial manufacturing facilities. This facilitates rapid and efficient transfer of the developed process to cGMP production.
See also
